We perform toxicological analyses on various biological matrices, using the CBA-N2a functional test : microalgae, fish, marine invertebrate, blood, etc.
The laboratory is also able to analyze samples for the detection of Saxitoxin (STX)-, Brevetoxin (PbTx)-, and Palytoxin (PLTX)-like activity.
Viallon, J., Chinain, M., Darius, H.T. (2020). Revisiting the neuroblastoma cell-based assay (CBA-N2a) for the improved detection of marine toxins active on voltage gated sodium channels (VGSCs). Toxins, 12 (5), 281. https://doi.org/10.3390/toxins12050281
Darius, H.T., Revel, T., Viallon, J., Sibat, M., Cruchet, P., Longo, S., Hardison, D.R., Holland, W.C., Tester, P.A., Litaker, R.W., McCall, J.R., Hess, P., Chinain, M. (2022). Comparative study on the performance of three detection methods for the quantification of Pacific ciguatoxins in French Polynesian strains of Gambierdiscus polynesiensis. Marine Drugs, 20 (6), 348. https://doi.org/10.3390/md20060348